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Updated: Jul 20, 2026
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| Certification Vendor: | ACRP (Association of Clinical Research Professionals) |
| Exam Name: | ACRP Certified Professional (ACRP-CP) Certification Exam |
| Exam Number: | ACRP-CP |
| Related Certifications: | ACRP Certified Clinical Research Coordinator (CCRC) ACRP Certified Clinical Research Associate (CCRA) |
| Exam Duration: | 180 minutes |
| Real Exam Qty: | Approximately 130 |
| Available Languages: | English |
| Exam Format: | Multiple choice, Computer-based testing |
| Recommended Training: | ACRP Official Training & Education |
| Exam Registration: | Pearson VUE Registration Portal ACRP Certification Page |
| Sample Questions: | ACRP ACRP-CP Sample Questions |
| Exam Way: | Computer-based exam delivered via test centers and/or remote proctoring through authorized testing provider |
| Pre Condition: | Professional experience in clinical research is typically required (commonly around 2–3+ years depending on eligibility pathway); eligibility requirements vary by pathway on the official ACRP certification policy. |
| Official Syllabus URL: | https://www.acrpnet.org/ |
| Section | Objectives |
|---|---|
| Topic 1: Regulatory Compliance | - Audit and inspection readiness - Regulatory documentation and submissions |
| Topic 2: Participant Safety and Protection | - Safety reporting and adverse events - Informed consent process |
| Topic 3: Study Operations | - Study planning and initiation - Study conduct and oversight |
| Topic 4: Clinical Research Foundations | - Good Clinical Practice (GCP) principles - Ethical conduct in clinical trials |
| Topic 5: Data and Quality Management | - Quality assurance and quality control - Clinical data management principles |
1. Which of the following reports should be retained in participant charts?
A) Safety reports
B) DSMB/IDMC reports
C) IRB/IEC progress reports
D) Lab reports
2. Per protocol, participants are scheduled to receive IP, which is calculated based on the participant's current weight. Unknown to the pharmacist, a participant recently lost 15 pounds and was overdosed as a result. What is the FIRST action the CRC must take to ensure the participant's safety?
A) Notify the sponsor.
B) Notify the PI.
C) Call the participant to return for an unscheduled visit.
D) Report a protocol deviation to the IRB/IEC.
3. The inclusion and exclusion criteria are in place so all subjects are:
A) Medically appropriate and protected from ethical vulnerability.
B) Healthy and willing to complete the clinical trial.
C) Patients with the disease under study and will not have any adverse events.
D) Ethically vulnerable and patients with the disease under study.
4. In preparation for an upcoming site audit, whose responsibility is it to ensure study-related functions were conducted by qualified personnel?
A) CRC
B) Sponsor
C) CRA
D) Investigator
5. At a close-out visit, which document should be retained only at the site?
A) Subject identification code list
B) Final trial close-out monitoring report
C) IP accountability
D) Treatment allocation
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: B | Question # 3 Answer: A | Question # 4 Answer: D | Question # 5 Answer: A |
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