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Updated: Jul 18, 2026
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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:
1. Bicarbonate and Chloride form an exchanger to help regulate and buffer the body's pH.
The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and:
A) Potassium
B) Sodium
C) Calcium
D) Chloride
2. If your reactions are strong at immediate spin (3+) and then get weaker at AHG (w+), it could mean the presence of a strong cold antibody.
Cold antibodies tend to be IgM and their optimum phase for reactivity is immediate spin. Incubation and washing of the sample may cause the agglutination that occurred at room temperature to break down. This would appear as a weaker reaction at AHG.
If the reaction strengths varied in each panel cell then that could be an indication that there are multiple antibodies present.
Your screen cells are 3+ at immediate spin and weak (W)+ at AHG. Your auto control is negative for both phases. Some of your antibody panel cells are 3+ at immediate spin and negative at AHG. What should you suspect?
A) A warm autoantibody is present
B) A cold antibody may be present
C) Bad specimen draw
3. Following an accidental needlestick, the person should be tested for all of the following except:
A) hepatitis A virus (HAV)
B) hepatitis B virus (HBV)
C) hepatitis C virus (HCV)
D) human immunodeficiency virus (HIV)
4. Antibodies are differentiated based on their heavy chains; different heavy chains create different isotypes.
Humans have five different isotypes of immunoglobulins.
Immunology
The part of the molecule responsible for differences among immunoglobulin classes is:
A) heavy chains
B) Fc
C) Hinge regions
D) light chains
E) Fab
5. The A and B antigens are present on the red cells of an AB patient. H antigen is a precursor to the ABO antigens.
An individual with type AB blood will demonstrate the complete absence of which of the following antigen sites?
A) A
B) H
C) None of the above
D) B
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: B | Question # 3 Answer: A | Question # 4 Answer: A | Question # 5 Answer: C |
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