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Last Updated: Aug 06, 2026

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Nursing ACNS Practice Q&A's

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Nursing ACNS Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Education and Research10-15%- Data Analysis and Outcome Measurement
- Research Utilization and Evidence Appraisal
- Clinical Scholarship and Publication
- Patient and Staff Education
Topic 2: Clinical Expertise in Adult Health40-50%- Pathophysiology and Clinical Management
- Health Assessment and Promotion
- Acute and Chronic Disease Management
- Therapeutic Interventions and Treatments
- Pharmacology for Adult Populations
- Diagnostics and Laboratory Interpretation
Topic 3: Leadership and Consultation15-20%- Quality Improvement and Patient Safety
- Consultation and Collaboration Skills
- Change Management and Innovation
- Healthcare Leadership Principles
- Interprofessional Team Collaboration
Topic 4: Systems and Outcomes10-15%- Healthcare Delivery Systems
- Regulatory Compliance and Standards
- Resource Management and Cost-Effectiveness
- Healthcare Informatics and Technology
- Risk Management and Quality Assurance
Topic 5: Foundations of Advanced Practice8-12%- Evidence-Based Practice Principles
- Advanced Practice Role Development
- Theoretical Foundations of Nursing
- Professional Ethics and Legal Issues
- Healthcare Policy and Advocacy

Nursing ANCC Adult Health Clinical Nurse Specialist Certification (ACNS) Sample Questions:

1. When counseling concerning the hepatitis B vaccination, the ACCRN understands that a contraindication is:

A) pregnancy and lactation
B) prior anaphylaxis or severe hypersensitivity
C) mild viral illness
D) history of poliomyelitis


2. Which of the following is a normal reaction to a Weber test?

A) Passive movement creates little resistance.
B) The patient hears the tuning fork laterally.
C) The patient hears the tuning fork in the midline.
D) The patient gags after the throat is stimulated.


3. When treating a patient who has an extremely high P.T. level from coumadin (warfarin) usage, the ACNS understands that which of the following is the antidote?

A) Vitamin C
B) Vitamin K
C) Vitamin D
D) Vitamin A


4. The CNS is prescribing a prostaglandin analog for his patient. Of the following, which would the CNS prescribe?

A) Zaditor 0.25%.
B) Travatan 0.004%.
C) Atropine.
D) Debrox 6.5%.


5. When evaluating a 56-year-old Caucasian female for menopause, the ACNS has knowledge that the primary function of FSH is:

A) triggering ovulation
B) stimulation of maturation of ovarian follicles
C) milk secretion
D) inhibiting release of LH from the pituitary gland


Solutions:

Question # 1
Answer: B
Question # 2
Answer: C
Question # 3
Answer: B
Question # 4
Answer: B
Question # 5
Answer: B

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