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SASInstitute A00-282 Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Apply Statistical Procedures for Clinical Trials15%- PROC MEANS, FREQ, TABULATE
- Basic statistical analysis for clinical data
Topic 2: Regulatory Submissions5%- Compliance for clinical data reporting
- ICH and FDA guidelines
Topic 3: Clinical Trials Data Structures10%- Define.xml and dataset specifications
- Clinical domain structures
- CDISC standards: SDTM, ADaM
Topic 4: Manage Clinical Trials Data5%- Clean, merge, and subset data
- Access and explore clinical datasets
- Use SQL and dictionary tables
Topic 5: Macro Programming for Clinical Trials15%- Debugging macros
- Create and call macros
- Macro variables and parameters
Topic 6: Transform or Summarize Clinical Trials Data15%- Aggregation and transposition
- Data step manipulation
- Derive variables and study days
Topic 7: Report Clinical Trials Results10%- Produce tables, listings, and figures
- PROC REPORT and PROC PRINT
Topic 8: Validate Clinical Trial Data Reporting20%- Validation principles
- Programming validation techniques
- Use PROC COMPARE and log review
Topic 9: Clinical Trials Process5%- Derive programming requirements from protocol and CRF
- Clinical trial lifecycle and protocol

SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

1. Which program will report all created output objects in the log?

A) ods trace=log; proc ttest data=WORK.DATA1; class TREAT; var RESULTS; run;
B) ods trace log; proc ttest data=WORK.DATA1; class TREAT; var RESULTS; run;
C) ods trace on; proc ttest data=WORK.DATA1; class TREAT; var RESULTS; run;
D) proc ttest data=WORK.DATA1 ods=trace; class TREAT; var RESULTS; run;


2. This question will ask you to provide a section of missing code.
Given the input SAS data set LABRAW:

Which DO LOOP will create the output SAS data set WORK.LAB_NEW?

A) do i=1 to 2; visit=i; date=dat{i}; result=num{i}; end; output;
B) do i=1 to 2; do j=1 to 2; visit=i; date=dat{j}; result=num{j}; end; output; end;
C) do i=1 to 2; do j=1 to 2; visit=i; date=dat{j}; result=num{j}; output; end;
D) do i=1 to 2; visit=i; date=dat{i}; result=num{i}; output; end;


3. A report that you are working on will require the following header lines:

Which code adds the second line of the header "Adverse Events"?

A) header2 'Adverse Events';
B) title2 'Adverse Events';
C) header2 = 'Adverse Events';
D) title2 = 'Adverse Events';


4. Given an existing work data set (DM), the following code is submitted:

A) MPRINT
B) MLOGIC
C) MRECALL
D) SYMBOLGEN


5. Which code segment would you use to derive the numeric variable AVAL from AVALC by stripping off non-numeric characters?

A) aval = put(compress(avalc, '<>='), best12.);
B) aval = put(substr(avalc, 2,2), best12.);
C) aval = input(substr(avalc, 2,2), best12.);
D) aval = input(compress(avalc, '<>='), best12.);


Solutions:

Question # 1
Answer: C
Question # 2
Answer: D
Question # 3
Answer: B
Question # 4
Answer: B
Question # 5
Answer: D

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