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SASInstitute A00-282 Exam Syllabus Topics:

SectionWeightObjectives
Macro Programming for Clinical Trials15%- Debugging macros
- Create and call macros
- Macro variables and parameters
Apply Statistical Procedures for Clinical Trials15%- PROC MEANS, FREQ, TABULATE
- Basic statistical analysis for clinical data
Transform or Summarize Clinical Trials Data15%- Aggregation and transposition
- Derive variables and study days
- Data step manipulation
Regulatory Submissions5%- ICH and FDA guidelines
- Compliance for clinical data reporting
Clinical Trials Process5%- Derive programming requirements from protocol and CRF
- Clinical trial lifecycle and protocol
Report Clinical Trials Results10%- Produce tables, listings, and figures
- PROC REPORT and PROC PRINT
Validate Clinical Trial Data Reporting20%- Use PROC COMPARE and log review
- Validation principles
- Programming validation techniques
Clinical Trials Data Structures10%- Clinical domain structures
- CDISC standards: SDTM, ADaM
- Define.xml and dataset specifications
Manage Clinical Trials Data5%- Access and explore clinical datasets
- Use SQL and dictionary tables
- Clean, merge, and subset data

SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

1. Which validation technique involves two programmers writing separate programs to produce the same output, then comparing the result?

A) Identical Programming
B) Peer Review
C) Peer Matching
D) Independent Programming


2. You are working on validating the ADSL data set which contains the variables subject, sex, age, birth date, baseline height, and baseline weight. These variables are brought in from SDTM, and you derive new variables baseline BMI (from baseline height and weight) and age categorization (from age).

You get the following in the SAS log:

To reconcile this difference, which variable values will be most helpful to provide to the production programmer?

A) BLBMI
B) SUBJID BLHT BLWT BLBMI
C) SUBJID BLBMI
D) AGECAT1 BLBMI


3. How does the code shown below help to validate report output?
data check;
set datlib.medhist;
mh_len = length(trim(mhcom1));
run;
proc freq data=check;
tables mh_len;
run;

A) It helps the programmer determine which observation has the longest value for mhcom1.
B) It writes all values of the mhcom1 variable that are longer than 200 in the results.
C) It shows all the values for mhcom1 in the results.
D) It shows all the values for the length of mhcom1 in the results.


4. Define.xml is an XML-based submission of a clinical study's:

A) metadata
B) data
C) results
D) protocol


5. Which is NOT required in the ADSL data set?

A) AGE
B) SITEID
C) FASFL
D) AGEU


Solutions:

Question # 1
Answer: D
Question # 2
Answer: B
Question # 3
Answer: D
Question # 4
Answer: A
Question # 5
Answer: C

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